Evaluation of the factors affecting the prognosis of patients with solid tumors and hematologic malignancies in the intensive care unit

Methods This study included patients who were hospitalized in Dokuz Eylul University Hospital Internal Medicine Intensive Care Unit for more than 24 hours during January 2012-December 2013 interval. The patients were divided into three groups; patients with solid tumors, patients with hematologic malignancies, and patiens without cancer. Their data was analyzed retrospectively. All patients ́ data (demographic data, organ failure, comorbid diseases, critical diseases, presence of infection, immunsupressive treatments within the last month) were recorded at the time of admittance.Additionally presence of remission, history of bone marrow transplantation, previous treatments, presence of neutropenia of patients with solid tumors and hematologic malignancies were also recorded. Results Mortality rate in intensive care unit was found to be %46.0 in general, %68.6 in patients with solid tumor, %53.0 in patients with hematologic malignancy, and % 39.8 in the control group (n = 512; solid tumor = 89, hematologic malignancy = 49, control group = 374). The mortality rate was especially high among patients with solid tumors. In the logistic regression model, APACHE II score and the need of invasive mechanical ventilation at the time of admission to intensive care unit were found as independent risk factors for increased mortality. In addition, the need of renal replacement therapy at the time of admission to intensive care unit was found as an independent risk factor for increased mortality among the control group.